Total synthesis of 20-norsalvinorin A. 1. Preparation of a key intermediate.
نویسندگان
چکیده
The key tricyclic intermediate 3a, for the total synthesis of the C(20)-nor analogue of salvinorin A, was prepared in seven steps from 3-furaldehyde. Key steps involved a highly regio- and diastereoselective Lewis acid assisted Diels-Alder reaction followed by base-promoted epimerization and a completely stereoselective conjugate reduction.
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عنوان ژورنال:
- The Journal of organic chemistry
دوره 74 6 شماره
صفحات -
تاریخ انتشار 2009